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PEA protects versus bacterial infection via innate immune modulation involving MCs, macrophages and microglia. Prophylactic PEA in a dose of 0.one mg/kg overall body weight prolonged survival rate and lessened neuro-inflammation in an aged murine bacterial meningitis product, while in the absence of antibiotics [forty two].The location is protected
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Within this assessment, we focus on the molecular targets of PEA, its pharmacological exercise in neurological Ailments, discomfort perception and inflammatory diseases, plus the latest proof over the efficiency of micronized and extremely‐micronized formulations of PEA when given by yourself or in combination Using the antioxidant flavonoids, in